The forerunner of Utica High School, the Utica Union School, opened in 1860. It was renamed Utica High School in 1900. The school was originally located within its namesake city of Utica, Michigan until 1955, when the construction of the current building was completed in Shelby Township. The former location is now home to Eppler Jr. High School.

Utica High School was the district’s original high school. It served as the sole high school until Henry Ford II, Stevenson, and Eisenhower High Schools opened in the late ’60s and ’70s